Dr Philippa Matthews

Senior Research Fellow

Philippa Matthews is a clinical research fellow working in the Nuffield Department of Medicine Research, funded by the Wellcome Trust. She is also an honorary consultant in Infectious Diseases and Microbiology at Oxford University Hospitals.

Philippa is the author of a range of academic articles spanning her interests in clinical infection, epidemiology, and immunology. She has written and illustrated a textbook aiming to make topics in infection interesting, memorable and accessible: Tropical Medicine Notebook (ISBN 9780198737773 https://global.oup.com/academic/product/tropical-medicine-notebook-9780198737773?cc=gb&lang=en&).

She is interested in public engagement work, and has received Wellcome funding for her ‘Viral Footprints’ project to inspire interest in science and medicine https://www.expmedndm.ox.ac.uk/viral-footprints.

Research Interests

Philippa’s research focuses on improving our understanding of the interplay between host and viral genetics in chronic viral infections, with particular interests in HIV and hepatitis B virus (HBV) in populations in sub-Saharan Africa.

She is also involved in a collaborative programme of work, funded by the BRC, to improve viral diagnostics in clinical laboratory practice, and is a member of the National Health Informatics Collaborative (NHIC) team to collate electronic clinical data for use in translational research.


Philippa supervises and co-supervises several students in the Nuffield Department of Medicine and Paediatrics. She delivers medical student teaching to undergraduate and postgraduate students through lectures, seminars, tutorials and on the wards, and is co-lead for the graduate medicine Infection and Immunity module. She contributes annually as an invited lecturer on the Diploma of Medical Care of Catastrophes (DMCC) course.

Selected articles

Hepatitis B virus infection as a neglected tropical disease. O’Hara GA, McNaughton AL, Maponga T, Jooste P, Ocama P, Chilengi R, Mokaya J, Liyayi MI, Wachira T, Gikungi DM, Burbridge L, O’Donnell D, Akiror CS, Sloan D, Torimiro J, Yindom LM, Walton R, Andersson M, Marsh K, Newton R, Matthews PC.

PLoS Negl Trop Dis. 2017;11(10):e0005842. doi: 10.1371/journal.pntd.0005842.

Hepitopes: A live interactive database of HLA class I epitopes in hepatitis B virus. Lumley S, Noble H, Hadley MJ, Callow L, Malik A, Chua YY, Duffey OJ, Grolmusova N, Kumar A, Ravenscroft S, Spencer JI, Neumann-Haefelin C, Thimme R, Andersson M, Klenerman P, Barnes E, Matthews PC. Wellcome Open Res. 2016;1:9. doi: 10.12688/wellcomeopenres.9952.1.

HLA-A is a Predictor of Hepatitis B e Antigen Status in HIV-Positive African Adults. Matthews PC, Carlson JM, Beloukas A, Malik A, Jooste P, Ogwu A, Shapiro R, Riddell L, Chen F, Luzzi G, Jesuthasan G, Jeffery K, Jojic N, Ndung’u T, Carrington M, Goulder PJ, Geretti AM, Klenerman P.,  J Infect Dis. 2016 15;213(8):1248-52. doi: 10.1093/infdis/jiv592. PMID: 2665530

Prevalence and Characteristics of Hepatitis B Virus (HBV) Coinfection among HIV-Positive Women in South Africa and Botswana.  Matthews PC, Beloukas A, Malik A, Carlson JM, Jooste P, Ogwu A, Shapiro R, Riddell L, Chen F, Luzzi G, Jaggernath M, Jesuthasan G, Jeffery K, Ndung’u T, Goulder PJ, Geretti AM, Klenerman P.  PLoS One. 2015 Jul 28;10(7):e0134037. doi: 10.1371/journal.pone.0134037. eCollection 2015.

Rolling back malaria.  Matthews PC.   eLife. 2015 Mar 30;4. doi: 10.7554/eLife.07364. PMID: 25822120

Human parvovirus 4 infection among mothers and children in South Africa.     Matthews PC, Sharp CP, Malik A, Gregory WF, Adland E, Jooste P, Goulder PJ, Simmonds P, Klenerman P.   Emerg Infect Dis. 2015 Apr;21(4):713-5. doi: 10.3201/eid2104.141545. No abstract available.  PMID: 25812109 Free PMC Article

Epidemiology and impact of HIV coinfection with hepatitis B and hepatitis C viruses in Sub-Saharan Africa.   Matthews PC, Geretti AM, Goulder PJ, Klenerman P.        J Clin Virol. 2014 Sep;61(1):20-33. doi: 10.1016/j.jcv.2014.05.018. Epub 2014 Jun 5. Review.     PMID: 24973812

For more information and a full list of publications, please visit:






Contact Details
Postal Address
Harris Manchester College
Mansfield Road
United Kingdom