Philippa Matthews

Research Fellow

Philippa Matthews is consultant in Infectious Diseases and Microbiology at Oxford University Hospitals, and a Nuffield Department of Medicine Research Fellow. She divides her time between clinical work and research, which is based at the Peter Medawar Building for Pathogen Research. Her D.phil and post-doctoral work mainly centred on studies of HIV immunology, but in August 2016, she is taking up a Wellcome Trust Intermediate Fellowship to develop her current programme of research focusing on chronic Hepatitis B infection.

She is interested in public engagement work, and contributes to workshops in primary and secondary schools to encourage and inspire students to consider careers in science and medicine.

Philippa is the author of a range of academic articles spanning her interests in clinical infection, as well as epidemiology, immunology and genetics of HIV and hepatitis viruses. She is currently writing a textbook, Tropical Medicine Notebook (currently in production, Oxford University Press).

Research Interests

Philippa’s current research focuses on improving our understanding of the interplay between host and viral genetics in chronic hepatitis B infection, aiming to define features of the immune response that contribute to viral control and clearance. She is currently setting up a new clinical cohort in South Africa.

In her clinical capacity, Philippa has contributed to research mainly in the fields of bone and joint infection, and antimicrobial prescribing and stewardship.

Teaching

Philippa delivers medical student teaching to undergraduate and postgraduate students in lectures, seminars, tutorials and on the wards. She contributes to school workshops run by the Royal College of Pathologists. She has recently been invited to contribute to lectures for the Diploma of Medical Care of Catastrophes (DMCC).

Selected articles:

HLA-A is a Predictor of Hepatitis B e Antigen Status in HIV-Positive African Adults. Matthews PC, Carlson JM, Beloukas A, Malik A, Jooste P, Ogwu A, Shapiro R, Riddell L, Chen F, Luzzi G, Jesuthasan G, Jeffery K, Jojic N, Ndung’u T, Carrington M, Goulder PJ, Geretti AM, Klenerman P.,  J Infect Dis. 2016 Apr 15;213(8):1248-52. doi: 10.1093/infdis/jiv592. Epub 2015 Dec 9. PMID: 26655301 Free PMC Article

Ongoing burden of disease and mortality from HIV/CMV coinfection in Africa in the antiretroviral therapy era. Adland E, Klenerman P, Goulder P, Matthews PC.  Front Microbiol. 2015 Sep 24;6:1016. doi: 10.3389/fmicb.2015.01016. eCollection 2015. Review.  PMID: 26441939 Free PMC Article

Prevalence and Characteristics of Hepatitis B Virus (HBV) Coinfection among HIV-Positive Women in South Africa and Botswana.  Matthews PC, Beloukas A, Malik A, Carlson JM, Jooste P, Ogwu A, Shapiro R, Riddell L, Chen F, Luzzi G, Jaggernath M, Jesuthasan G, Jeffery K, Ndung’u T, Goulder PJ, Geretti AM, Klenerman P.  PLoS One. 2015 Jul 28;10(7):e0134037. doi: 10.1371/journal.pone.0134037. eCollection 2015.

Rolling back malaria.  Matthews PC.   life. 2015 Mar 30;4. doi: 10.7554/eLife.07364. No abstract available.   PMID: 25822120 Free PMC Article

Human parvovirus 4 infection among mothers and children in South Africa.     Matthews PC, Sharp CP, Malik A, Gregory WF, Adland E, Jooste P, Goulder PJ, Simmonds P, Klenerman P.   Emerg Infect Dis. 2015 Apr;21(4):713-5. doi: 10.3201/eid2104.141545. No abstract available.  PMID: 25812109 Free PMC Article

Screening and treatment for hepatitis C: a balanced perspective.   Matthews PC, Jeffery K, Klenerman P, Barnes E, Cooke G.      BMJ. 2015 Feb 24;350:h644. doi: 10.1136/bmj.h644. No abstract available.   PMID: 25711895

Epidemiology and impact of HIV coinfection with hepatitis B and hepatitis C viruses in Sub-Saharan Africa.   Matthews PC, Geretti AM, Goulder PJ, Klenerman P.        J Clin Virol. 2014 Sep;61(1):20-33. doi: 10.1016/j.jcv.2014.05.018. Epub 2014 Jun 5. Review.     PMID: 24973812

For a full list of publications, please visit: https://www.researchgate.net/profile/Philippa_Matthews

 

 

Contact Details
Postal Address
Harris Manchester College
Mansfield Road
Oxford
OX1 3TD
United Kingdom